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Impact of microbiota on central nervous system and neurological

WebAbundant and diverse microbial communities coexist in humans and mice. Majority of these microorganisms including bacteria, archaea, fungi, and viruses reside in …

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URL: https://jneuroinflammation.biomedcentral.com/articles/10.1186/s12974-019-1434-3

The function of gut microbiota in immune-related neurological …

WebThe GI tract is a highly complex organ composed of microorganisms, the intestinal epithelium, and the mucosal immune system. The microorganisms living in the …

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Headache and immunological/autoimmune disorders: a …

WebIn a recent study involving 60,436 US adults aged ≥18 years participating in the 2015 and 2016 National Health Interview Survey (NHIS), a higher prevalence of age …

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A tale of two transmitters: serotonin and histamine as in vivo

WebStress-induced mental illnesses (mediated by neuroinflammation) pose one of the world’s most urgent public health challenges. A reliable in vivo chemical biomarker …

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Exercise suppresses neuroinflammation for alleviating Alzheimer’s

WebIn 2020, the World Health Organization (WHO) proposed that all adults should have 150–300 min of moderate-intensity physical activity or 75–150 min of …

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Microglia in depression: an overview of microglia in the …

WebMajor depressive disorder (MDD) is a public health problem that affects approximately 322 million people worldwide [].During the coronavirus disease 2019 …

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NAD+ improves cognitive function and reduces …

WebNAD + treatment mitigated impairment of learning and memory in CCH rats. The BCCAO model is a classic animal model that mimics CCH. After the BCCAO …

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Peripheral blood amyloid-β involved in the pathogenesis of …

WebAlzheimer’s disease (AD) is the most common age-associated dementia with progressive loss of memory and cognitive functions [].It is predicted that by 2050, …

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Altered substrate metabolism in neurodegenerative disease: new …

WebNeurodegenerative diseases (NDs), such as Alzheimer’s disease (AD), Parkinson’s disease (PD) and multiple sclerosis (MS), are relatively common and …

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Exercise mimetics: a novel strategy to combat neuroinflammation …

WebAs our society continues to age, we face more challenges from diseases and healthcare costs, especially neurodegenerative disease [1, 2]; for example, Alzheimer’s …

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Chronic stress-induced depression requires the recruitment of

WebDepression is a recurrent and devastating mental disease that is highly prevalent worldwide. Prolonged exposure to stressful events or a stressful environment …

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Obesity-induced blood-brain barrier dysfunction: phenotypes and

WebObesity, a burgeoning global health issue, is increasingly recognized for its detrimental effects on the central nervous system, particularly concerning the integrity of …

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The progress of gut microbiome research related to brain disorders

WebThere is increasing evidence showing that the dynamic changes in the gut microbiota can alter brain physiology and behavior. Cognition was originally thought to …

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Neural networks and the anti-inflammatory effect of …

WebIn 1990, the World Health Organization recognized auricular acupuncture as a microacupuncture system that can have a positive impact on regulating whole-body …

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Inflammation: the link between comorbidities, genetics, and …

WebAlzheimer’s disease (AD) is a neurodegenerative disorder, most cases of which lack a clear causative event. This has made the disease difficult to characterize …

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Prehabilitative resistance exercise reduces neuroinflammation and

WebResistance training enhanced the muscle strength and cognitive performance in 9-month and 18-month-old mice. a A picture of resistance exercise training …

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Gut microbiota, circulating cytokines and dementia: a Mendelian

WebSome studies have shown that gut microbiota may be associated with dementia. However, the causal effects between gut microbiota and different types of …

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The cerebrovascular and neurological impact of chronic smoking …

WebTraumatic brain injury (TBI) has long been among the most common type of trauma and the leading cause of death and disability in the young-aged population (≤ 45 …

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The peri-menopause in a woman’s life: a systemic inflammatory …

WebThe peri-menopause or menopausal transition—the time period that surrounds the final years of a woman’s reproductive life—is associated with profound …

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Central intracrine DHEA synthesis in ageing-related …

WebIt is a well-known fact that DHEA declines on ageing and that it is linked to ageing-related neurodegeneration, which is characterised by gradual cognitive decline. …

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Neuroinflammation and psychiatric illness Journal of

WebMultiple lines of evidence support the pathogenic role of neuroinflammation in psychiatric illness. While systemic autoimmune diseases are well-documented causes of …

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