Horizondiscovery.com

Gene editing and gene modulation for life sciences

WEBHorizon Discovery drives the application of gene editing and gene modulation to enable world-leading academic institutes, pharmaceutical and biotechnology companies, as …

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URL: https://horizondiscovery.com/

Medical Device Innovation Consortium Launches Initiative to …

WEBInitiative to develop, manufacture, and validate publicly available somatic reference samples and create public genomic datasets with the potential to be used by …

Category: Health Go Health

siRNA solutions by Dharmacon™

WEBRNA interference via synthetic small interfering RNA (siRNA) is the preferred choice for fast but reliable loss-of-function studies. Broadly useful across many applications and in any …

Category: Health Go Health

Dharmacon Reagents Infinite reliability for functional genomics

WEBUnderstanding functional genomics is critical to advance genetic research and therapeutic discovery. Dharmacon Reagents support researchers on this journey at the DNA, RNA, …

Category: Health Go Health

Detecting RNA fusions in cancer

WEBThe challenges. RNA-Seq can potentially lead to false-negative results. Poor quality RNA will decrease the number and quality of reads, which reduces the likelihood of detecting …

Category: Health Go Health

MDIC Partners with HD to Improve Accuracy of Next Generation …

WEBInitiative to focus on development, manufacture, and validation of publicly available somatic reference samples. ARLINGTON, Va.--(BUSINESS WIRE)--The …

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Strategies to detect and validate your CRISPR gene edit

WEBA. Mismatch detection assay 1,2. Insertion or deletion (INDEL) Endonucleases such as T7 endonuclease I recognize structural deformities in DNA heteroduplexes. Cleavage …

Category: Health Go Health

Autophagy Pathway

WEBAs demonstrated by the 2016 Nobel Prize winner, Yoshinori Ohsumi, autophagy is a fundamental process vital to cellular health. The molecular processes and signalling …

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Molecular reference standards

WEBBenefits of Revvity Mimix reference standards. Available in gDNA, FFPE, cell-free DNA and formalin-compromised DNA formats. Cell line-derived to ensure genomic complexity is …

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Therapeutic promise of base editing

WEBFigure 1a. (from Nature publication Newby et al.) The edited region of HBB with the target A at protospacer position 7 shown in blue along with potential bystander …

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SMARTvector Inducible Lentiviral shRNA

WEBAn Optimized Inducible Gene Silencing System in a Single Vector. The SMARTvector Inducible Lentiviral shRNA vectors incorporate the Tet-On® 3G bipartite induction …

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Colorectal cancer: making a global challenge patient-centric

WEBColorectal cancer (CRC) is the abnormal cell growth starting in the lining of the large intestine or rectum 1.In the UK CRC is the 4 th most common type of cancer diagnosed …

Category: Cancer Go Health

Pooled Lentiviral Screening Libraries

WEBScreen 100s or 1000s of genes without the need for costly automation. Use pooled lentiviral screens to identify genes that regulate cellular responses and signaling pathways, or to …

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shMIMIC Lentiviral microRNA

WEBshMIMIC Lentiviral microRNAs were developed using a unique and proprietary design strategy resulting in highly functional microRNA mimics. shMIMIC lentiviral microRNA …

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Pin-point™ Reagents

WEBRevvity's Pin-point base editing technology is a three-component system featuring a nickase Cas9 which recruits the effector deaminase through fusion to an aptamer-binding protein. The aptamer is linked to the guide RNA associated with the nuclease in an extended, chimeric RNA scaffold. The modular nature of effector recruitment means that

Category: Health Go Health

Webinar: CHOSOURCE advances biotherapeutic production

WEBOptimizing Biotherapeutic Cell Lines for Continuous Manufacturing. CHOSOURCE advances biotherapeutic production: a three-part customer webinar series detailing …

Category: Health Go Health