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Ageless: The New Science of Getting Older Without Getting Old

WEBAgeless: The New Science of Getting Older Without Getting Old is a forthcoming book discussing the aging research community and its newfound interest in …

Actived: 5 days ago

URL: https://www.fightaging.org/archives/2021/01/ageless-the-new-science-of-getting-older-without-getting-old/

Resting Metabolic Rate in Aging and Age-Related Disease

WEBResting metabolic rate declines with age, a situation that has evolved for perhaps much the same reasons as loss of stem cell function, in that it is one part of the …

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Building Aging Clocks for Specific Organs from Circulating Protein

WEBWe discovered nearly 20% of the population show strongly accelerated age in one organ and 1.7% are multi-organ agers. Accelerated organ aging confers 20-50% …

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Reviewing the Mitochondrial Contribution to Aging and Age …

WEBThere are two ways we might think of mitochondria in the context of aging. The first is the SENS view of the mitochondrial contribution to aging. The mitochondrial …

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Trends in Human Healthspan versus Lifespan – Fight Aging!

WEBAging is damage, and the body fails in the same way that any complex, damaged machine fails.If one slows the pace of damage accumulation, as technological progress over the past century has achieved to a modest degree, albeit by accident rather than intent, both overall life span and the time spent in a period of damage and …

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The Effects of Exercise on Bone Marrow – Fight Aging!

WEBAn interesting discovery, and one more benefit of exercise: "researchers have found one more reason to exercise: working out triggers influential stem cells to become …

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Long Term Effects on Health: is it the Sitting, or the Immobility

WEBSitting for long periods not bad for health. New research has challenged claims that sitting for long periods increases the risk of an early death even if you are …

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Announcing the Academy for Health and Lifespan Research

WEBA group of leading scientists devoted to research on the mechanisms of biological aging today announced the formation of the Academy for Health and …

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Worldwide Trends in Healthy versus Unhealthy Remaining Life …

WEBProportion of Years in Ill Health at age 60 (PYIH-60), meaning (LE-60 - HALE-60) / LE-60, has been used to calculate the "unhealthy" years proportion in life …

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Aging is Not a Disease (But We Need to Treat It Anyway)

WEBDisease is a much abused word, and the boundaries of its varied meanings to different groups shift over time. Most of the well-known failures that occur in organs and other biological systems over the later stages of aging are referred to as diseases, but are in fact better designated as medical conditions.

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Overhyping the Effects of Hyperbaric Oxygen Treatment on Aging

WEBPer the paper, hyperbaric oxygen treatment causes average telomere length to grow by ~20% and markers of cellular senescence to decrease by ~35% in …

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XPRIZE Healthspan, $101 Million to Incentivize Rejuvenation in Old

WEBXPRIZE, the world's leader in designing and operating large-scale incentive competitions to solve humanity's grand challenges, today launches $101M XPRIZE …

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Towards Adjustment of the Gut Microbiome to Slow Aging

WEBThis paper makes the reasonable argument that means of modestly slowing aging will emerge from ways to reverse age-related changes in the varied microbial …

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A Call to Focus on Extension of Healthspan, Not Lifespan

WEBExtension of healthy life span is inextricably linked with extension of overall life span when following a repair strategy. Health persists until unrepaired damage …

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Towards a Practical, Palatable Low Methionine Diet

WEBLow methionine intake has been shown, in animal studies, to mimic many of the same effects of calorie restriction, which is to say improved health and extended life span.A sizable fraction of the trigger mechanisms that produce improved metabolism as a result of lowered calorie intake appear to depend on methionine levels. Attempting a …

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Reviewing the Clinical Evidence for NAD+ Upregulation

WEBNAD upregulation prevents actinic keratosis and improves some measures of photoaging. While the mechanisms of action are not fully understood, NAD is a co …

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The Documentary “How to Live Forever” – Fight Aging!

WEBBiomedical gerontologist Aubrey de Grey is one of the figures appearing in the documentary film "How to Live Forever." It's played straight but isn't a serious piece, …

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Reviewing the Potential for Klotho as a Basis for Therapy

WEBKlotho is one of the few robustly longevity-associated genes discovered over the past few decades. Increased levels of the circulating α-klotho protein slows aging in …

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The Cost of Aging-Induced Chronic Disease – Fight Aging!

WEBFrom In Search of Enlightenment: "On this WHO website the fact that chronic disease killed 9 million people under the age of 60 last year is highlighted. This …

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Reporting on the Aging Research and Drug Discovery Meeting …

WEBEarlier this year the Aging Research and Drug Discovery meeting was organized as a part of the broader BASAL LIFE scientific conference. As is traditional for …

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Survival and Longevity: Why Bother

WEBIn the case of rejuvenation research, there are obvious and compelling reasons to work on technologies to halt and reverse degenerative aging even absent a will to avert death. Rejuvenation treatments are the only long-term reliable solution to prevent the great suffering, pain, and cost that comes with aging while still alive.

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Altos Labs Officially Launches with $3 Billion in Funding to Tackle …

WEBAltos Labs was formed to develop in vivo reprogramming into a viable class of therapies to treat aging. Reprogramming occurs during embryonic development, and …

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