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The Immune System and Aging

WebAn antigen is a part of a pathogen, cell, or protein that acts as a target for the immune system. These are molecules that the immune system recognizes as foreign or “non-self” …

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URL: https://immunologyexplained.aai.org/the-immune-system-and-aging/

The Future of Undergraduate Immunology Education: Can a …

WebThe field of immunology is rapidly evolving and has significant relevance to understanding human health, particularly in light of the threat from infectious diseases …

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Metabolic Shifts in Immunity and Inflammation The Journal of

WebOngoing inflammatory and immune responses are associated with dramatic shifts in tissue metabolism. These changes include local depletion of nutrients, increased …

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The American Association of Immunologists

WebPolio: Part III—The Vaccine. by John S. Emrich and Charles Richter July 2021, page 24–29. Once John F. Enders (AAI 1936, AAI president from 1952–53), Thomas Weller (AAI …

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The American Association of Immunologists

WebFormative Years Polio: Part I. by John S. Emrich and Charles Richter December 2020. In the late 19th century, sporadic outbreaks of a perplexing and debilitating disease began …

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Of Mice and Not Men: Differences between Mouse and Human …

WebMice are the mainstay of in vivo immunological experimentation and in many respects they mirror human biology remarkably well. This conservation of function is …

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Leadership in Science Award

WebAnthony S. Fauci Honored with the AAI Exceptional Leadership in Science Award Anthony S. Fauci, M.D., DFAAI (AAI ’73), Director, National Institute of Allergy and Infectious …

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The Central Role of the Alternative Complement Pathway in …

WebThe complement system is one of the major means by which the body recognizes foreign Ags and pathogens (reviewed in Refs.1 and 2).The major function of …

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A Chronological Overview of Hawai‘i and Public Health

WebEstimates of the native population in 1778 range from 300,000 to nearly 700,000. Just 40 years later, the figure had dropped to about 150,000, and by 1900, to only 28,800. …

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The Role of the Transcription Factor CREB in Immune Function

WebCREB is a transcription factor that is known for its role in cell proliferation, differentiation, and survival (1–3).However, emerging evidence has revealed specific …

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Psychological Stress in Children May Alter the Immune Response

WebPsychological stress is a public health issue even in children and has been associated with a number of immunological diseases. The aim of this study was to …

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Hero Horses in the Fight Against Disease

WebHero Horses in the Fight Against Disease. by Charles Richter and John Emrich October 2021. Painting depicting diphtheria, c. 1912 Wellcome CollectionIn the December 10, …

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Antigen and Immunogen: An Investigation into the Heterogeneity …

WebUnderstanding immunology is critical for training the next generation of scientists and medical practitioners (), but the point at which students first encounter key …

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The Minority Scientists’ Experience: Challenging and Overcoming

WebAddress correspondence and reprint requests to Dr. Tonya J. Webb, Department of Microbiology and Immunology, University of Maryland School of Medicine …

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How Honolulu’s Chinatown "Went Up in Smoke"

WebKaumakapili Church after the fire, 1900 Hawai'i State ArchivesBubonic plague (Yersinia pestis), responsible for the worst pandemics in history, was unknown in Hawai‘i until the …

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M1 Means Kill; M2 Means Heal

WebMills’ observation that macrophages could promote or inhibit cancer growth dates back even farther, and this outcome was found to correlate with the way …

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Enzyme-Linked Immunosorbent assay determination of …

WebThe major function of IgA is to prevent bacteria from binding to the mucous membrane and to prevent viruses from multiplying and killing membrane cells. It is estimated that in a …

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Influenza Pathogenesis: The Effect of Host Factors on Severity of

WebAdaptive immune responses play a key role in protection against IAV infection and disease (previously reviewed in Ref. 1–6).The humoral immune response …

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Recent Advances in the Development of Monoclonal Antibodies …

WebIt has been reported that Abs can provide protection using a variety of mechanisms, including neutralization, opsonization, complement activation, and Ab …

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