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Caelus Health – Microbiome Therapeutics for Type 2 Diabetes …

Details: Caelus Health is an Amsterdam-based biotech company with in-depth knowledge of the microbiome, dedicated to the development and commercialization of microbiota-based products to prevent and treat cardiometabolic disorders, including Diabetes, and other unmet medical needs. The company has built a strong patented-protected proprietary position

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Caelus Health – Caelus Health

Details: Pim W. Gilijamse et al. NPJ Biofilms and Microbiomes 2020: Treatment with E. hallii: a pilot study of safety and dose-response effects on glucose metabolism in …

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contact – Caelus Health

Details: Pim W. Gilijamse et al. NPJ Biofilms and Microbiomes 2020: Treatment with E. hallii: a pilot study of safety and dose-response effects on glucose metabolism in …

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DIABETES MELLITUS

Details: DIABETES MELLITUS. Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose (or blood sugar), which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The most common is type 2 diabetes, usually in adults, which occurs when the body becomes resistant to insulin or doesn’t

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Intestinal microbiota and faecal transplantation as treatment …

Details: health in order to eventually prevent disease progression. In this respect, faecal transplantation studies have implicated that butyrate-producing intes-tinal bacteria are crucial in this process and be considered as key players in regulating diverse signalling cascades associated with human glucose and lipid metabolism.

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Caelus Health and Nestlé Health Science sign exclusive global …

Details: Nestlé Health Science (NHSc), a wholly-owned subsidiary of Nestlé, is a globally recognized leader in the field of nutritional science. At NHSc we are committed to empowering healthier lives through nutrition for consumers, patients and their healthcare partners. We offer an extensive consumer health portfolio of

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Fecal microbiota transplantation in human metabolic diseases: …

Details: bolic health and diet of the FMT donor is assessed and via which route the FMT procedure is performed. In this review, we will crit-ically appraise the efficacy and effect size of treatment of FMT in human disease, discuss its major pitfalls, and provide a roadmap of how the FMT procedure may be further standardizedand opti-

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Live Biotherapeutic Products, A Road Map for Safety …

Details: health and how LBPs may exert their beneficial effect. As mentioned, LBPs do not exert their biological effects by reaching distant organs, tissues or receptors, and, in most cases, do not act directly on a known target, but are thought to exert their …

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acetate by commensal Anaerostipes associates with host health

Details: important health benefits to the host1. One of the major functions of the intestinal microbes is the biosynthesis of absorbable metabolites conferring effects on intestinal epithelia and beyond2. Most studied are the short chain fatty acids (SCFAs) …

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Faecal microbiota transplantation halts progression of human …

Details: Faecal microbiota transplantation halts progression of human new-onset type - Caelus Health 10 Diabetes.

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PRESS RELEASE Chr. Hansen enters first collaboration on …

Details: Health have identified and patented a single species, E. hallii, which through preclinical studies has proven to be capable of reducing insulin resistance, a primary symptom of type 2 diabetes. Caelus’ lead strain, CP-001, is a formulation of E. hallii and is currently in phase I clinical study.

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FOR PATIENTS – Caelus Health

Details: Caelus Health is a Dutch life sciences company dedicated to developing a new class of products to increase the sensitivity for insulin and aiming to delay the onset of Type 2 Diabetes in people who are overweight and have an increased risk for diabetes and cardiovascular disorders.

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Press release PROMISE final EN

Details: About Caelus Health: Caelus Health is an Amsterdam-based biotech company. Caelus is dedicated to the development and commercialisation of functional food and pharmaceutical products for the prevention and early treatment of cardio-metabolic diseases. Based on the

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Caelus Health announces first closing of a Series A financing …

Details: Caelus Health is one of the first companies fully dedicated to the clinical development of microbiota-based products for early intervention in cardio-metabolic disease. Caelus was founded in 2014 by prof. Max Nieuwdorp (Academic Medical Centre, AMC, Amsterdam) and prof. Willem M. De Vos (Wageningen University), based on

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Treatment with Anaerobutyricum soehngenii: a pilot study of …

Details: microbiota composition, Anaerobutyricum spp. growth rates, and persistence of administered A. soehngenii up to 2 weeks after cessation of treatment were measured.

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Durable coexistence of donorand recipient strains after fecal …

Details: Health (grant R01GM092802). We thank the staff of beamline X10SA of the Swiss Light Source for assistance. Parts of the experiments were performed on beamlines ID29, ID23.1, and ID23.2 at the European Synchrotron Radiation Facility, Grenoble, France. We are grateful to beamline scientists for providing

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PRESS RELEASE August 10, 2021

Details: metabolic health in a mouse model. Of note, the new genes for this pathway were enriched in the gut microbiota of healthy subjects as compared to patients with type 2 diabetes.” Wageningen University & Research is a strategic partner of Caelus Health in the identification,

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Author(s) 2020 Towards an EU-wide suitable regulatory …

Details: Regulation is critical to ensure the safety of health-care products, including those based on human stool. The existing Directive 2001/83/EC covers the use of ‘industrially processed’ products based on human stool, making them medicinal products. Efforts should be made to set an EU-wide harmonisation regu-

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Donor Fecal Microbiota Transplantation Alters Gut Microbiota …

Details: stock in, consult for, and has intellectual property rights in Caelus Health. He consults for Kaleido. None of these are directly relevant to the current paper. Wites, smits, et al. Hepatology CommuniCations, month 2020 2 abnormalities ranging from simple steatosis (non-

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Production of butyrate from lysine and the Amadori product …

Details: as energy source by enterocytes thus influencing colonic health. However, the pathways and the identity of bacteria involved in this process remain unclear. Here we describe the isolation from the human intestine of Intestinimonas strain AF211, a bacterium that can convert

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PRESS RELEASE March 1, 2016

Details: Caelus Health is an Amsterdam-based biotech company. Caelus is dedicated to the commercialisation of functional food and pharmaceutical products for the prevention and early treatment of cardio-metabolic diseases. Based on the strong correlation between the intestinal microbiome and health, the company is developing an entirely new class of

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Fecal Microbiota Transplantation from Overweight or Obese …

Details: 1 CLINICAL CANCER RESEARCH | TRANSLATIONAL CANCER MECHANISMS AND THERAPY 2 3 Q1 Fecal Microbiota Transplantation from Overweight or 4 Obese Donors in Cachectic Patients with Advanced 5 GastroesophagealCancer:ARandomized,Double-blind, 6 Q2 Placebo-controlled, Phase II Study 7 Nicolien C. de Clercq1, Tom van den Ende2, Andrei …

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