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Genetics and Public Health

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Nodular sclerosis classical Hodgkin lymphoma (NScHL)

Web ResultClassical Hodgkin lymphoma is a distinct neoplastic entity with heterogeneous epidemiological features. It accounts for approximately 10% of all …

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Classification of Hodgkin lymphoma over years

Web ResultHistologic classification of Hodgkin lymphoma (HL) evolved through different systems, starting from the modern histologic classifications by Jackson …

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Chronic Myelomonocytic Leukemia (CMML)

Web ResultChronic myelomonocytic leukemia (CMML) is the most frequent entity among myeloproliferative / myelodysplastic syndromes, as defined by the World …

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Florid follicular hyperplasia PTLD

Web ResultPhenotypically, FFH PTLD cases show follicular hyperplasia and the size of the follicles varied, but they all contained large, polarized, germinal centers …

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Follicular lymphoma (FL)

Web ResultNo fusion protein. The t(14;18) brings about the juxtaposition of BCL-2 with the Ig heavy chain joining segment, with consequent marked overexpression of the …

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An Introduction to Chromosomal Aberrations

Web ResultSince the chromosome we see and score at metaphase has two (sister-) chromatids, it is convenient (and conventional) to divide all aberrations into two broad types: …

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+7 or trisomy 7 (solely)

Web ResultTrisomy 7 is a common finding in benign and malignant solid tumors, in several non-neoplastic lesions (for example, osteoarthritis and rheumatoid arthritis), and in …

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del (5q) solely in Myelodysplastic syndrome

Web ResultMyelodysplastic syndrome (MDS) with isolated deletion of chromosome 5q is part of a group of clonal disorders in myeloid stem cells with ineffective …

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Mixed phenotype acute leukemia (MPAL)

Web ResultMixed phenotype acute leukemia (MPAL) accounts for 2-5% of all acute leukemias (Weinberg OK et al., 2010). The World Health Organization …

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Head and Neck: Squamous cell carcinoma: an overview

Web ResultThe most important risk factors for developing HNSCC are tobacco smoking and alcohol consumption, which have a synergistic effect. Smoking …

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Lymphocyte-rich classical Hodgkin lymphoma

Web ResultHodgkin lymphoma (HL) has been classified into classical HL (cHL) (Stein et al., 2008), which accounts for 95% of all cases, and the less common nodular …

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Atlas of Genetics and Cytogenetics in Oncology and Haematology

Web ResultAtlas of Genetics and Cytogenetics in Oncology and Haematology

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A Proposal for Training Medical Students : Knowing and Caring for …

Web ResultIn an analytical survey of the handicapped population, it was shown for children that 56% are mentally handicapped, 7% are poly-handicapped, 18% have …

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del(5q) in myeloid neoplasms

Web ResultAdditional anomalies. By definition, an interstitial deletion of 5q must be the sole abnormality for 5q- syndrome. However, 5q deletion can be seen with other …

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Mixed cellularity classical Hodgkin lymphoma (MCcHL)

Web ResultMost patients affected by mixed cellularity (MC) classical Hodgkin lymphoma (cHL) present with B symptoms and in intermediate stages (II and III), …

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Atypical Chronic Myeloid Leukemia (aCML)

Web ResultaCML is a chronic myeloproliferative disorder with a clinical and hematological picture similar to chronic myelogenous leukemia (CML) but lacking Philadelphia …

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